A randomised controlled trial of vaporised Δ9-tetrahydrocannabinol and cannabidiol alone and in combination in frequent and infrequent cannabis users

1/19/19–A randomized placebo controlled trial was conducted to examine the acute effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) alone and in combination when administered by vaporization to frequent and infrequent marijuana users. CBD showed some intoxicating properties relative to placebo. Low doses of CBD when combined with THC enhanced, while high doses of CBD reduced the intoxicating effects of THC. Read