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Frequent teenage cannabis use: Prevalence across adolescence and associations with young adult psychopathology and functional well-being in an urban cohort

11/1/21--This study aims to 1) examine the prevalence of cannabis use during adolescence, and 2) investigate links of frequent (i.e., weekly or daily) teenage cannabis use with psychopathology and functional well-being at age 20—compared to no or occasional use. Results indicate that frequent teenage cannabis use was common and associated with problematic substance use, more delinquency, and poorer functional well-being at age 20. Accordingly, frequent teenage cannabis users could experience increased difficulties in mastering the transitions of young adulthood. Read

Substance use screening and rates of treatment referral among justice-involved youth

8/30/21--Data on screening and linkage to treatment within the justice system is lacking. Therefore, to further inform the juvenile justice behavioral health cascade of care, this study examined factors associated with identified problematic substance use and treatment referral using two screening tools. Study results indicates that regardless of tool used, treatment referral was low, highlighting the need for accurate identification of treatment needs of substance-using, justice-involved youth. Interventions to facilitate referrals for youth with problematic substance use are needed. Read

Changes in cannabis use modes among Canadian youth across recreational cannabis legalization: Data from the COMPASS prospective cohort study

8/2/21--This study was designed to investigate changes in cannabis modes of use and associated factors across the federal legalization of recreational cannabis use for adults in Canada. Results indicate that multi-modal cannabis use increased among Canadian youth, and its association with other substance use and depressive symptoms may indicate clustering of additional harms. Read

A longitudinal analysis of e-cigarette use and cigar, little cigar or cigarillo initiation among youth and youth adults: 2017-2019

7/28/21--This study was designed to examine whether youth and young adult e-cigarette use is associated with initiation of cigars, little cigars, or cigarillos (CLCCs) and current use of flavored CLCCs. Study results raises new concerns about the effects of e-cigarette use on subsequent combustible tobacco use; therefore, restrictions on CLCCs should be considered in conjunction with current policies designed to reduce the youth vaping epidemic. Read

Adolescent drug use before and during U.S. national COVID-19 social distancing policies

7/27/21--This study was designed and conducted to examine how adolescent substance use and perceived availability of substances have changed during the COVID-19 pandemic. Results from longitudinal data indicate that perceived availability of marijuana, alcohol, and vaping devices declined at historic rates during the pandemic of 2020. Lack of accompanying reductions in prevalence for marijuana and binge drinking demonstrates the substantial challenges facing a supply-side approach to the reduction of adolescent use of these substances. Read

Adolescent drug use before and during U.S. national COVID-19 social distancing policies

6/21/21--A study designed to examine how adolescent substance use and perceived availability of substances have changed during the COVID-19 pandemic has concluded that perceived availability of marijuana, alcohol, and vaping devices declined at historic rates during the pandemic of 2020. Lack of accompanying reductions in prevalence for marijuana and binge drinking demonstrates the substantial challenges facing a supply-side approach to the reduction of adolescent use of these substances. Read

Increases in frequent vaping cannabis among high school seniors in the United States 2018-2019

5/7/21--In a study comparing and examining the prevalence of self-reported frequent vaping of cannabis (defined as using ≥10 times in the past month) between 2018 and 2019 cohorts, frequent vaping of cannabis is increasing among adolescents in the United States, particularly among selected subgroups. Read

Chapter Six – Exposure to drugs of abuse induce effects that persist across generations

4/29/21--This segment of the study highlights intergenerational and transgenerational phenotypes in offspring following a history of parental drug exposure. Special attention is paid to parental preconception exposure studies of five drugs of abuse (alcohol, cocaine, nicotine, cannabinoids, and opiates) and associated behavioral and physiological outcomes in offspring. The highlighted studies demonstrate that parental exposure to drugs of abuse has enduring effects that persist into subsequent generations. Read

Cannabis legalization and link to increase in fatal collisions

4/6/21--Legalization of recreational cannabis may be associated with an increase in fatal motor vehicle collisions based on data from the United States, and authors discuss the implications for Canada in an analysis in CMAJ (Canadian Medical Association Journal). Read

Supersized alcopop related calls in the National Poison Data System, 2010-2019

3/23/21--The current study examined the characteristics of calls to U.S. poison control centers involving supersized alcopops, in addition to comparing the proportion of calls for underage consumers between calls involving consumption of supersized alcopops and calls involving other types of alcohol. Results indicate that compared to other alcohol products, calls to U.S poison control centers for supersized alcopops disproportionately involved underage drinkers. To protect youth, improved regulation of supersized alcopop products is urgently needed. Read

Cannabis, vaping, and respiratory symptoms in a probability of U.S. youth

3/3/21--This study provides preliminary evidence that adolescents' cannabis use with Electronic nicotine delivery systems (ENDS) may have negative health consequences. Lifetime cannabis use with ENDS was substantially associated with higher odds of respiratory symptoms. Read

Radical technological breakthroughs in drugs and drug markets: The cases of cannabis and fentanyl

2/12/21--This essay explores possible future consequences of trends related to cannabis legalization and the arrival of nonmedical fentanyl fundamentally altering North American drug markets. Read

Adolescent drug use initiation and transition into other drugs

2/1/2021--According to a retrospective longitudinal examination across race/ethnicity, adolescents’ initial use of marijuana and inhalants may lead to substantial risks of using other drugs over time. It is therefore important to screen adolescent drug use comprehensively and provide early interventions to prevent an escalation to more detrimental drugs. The findings provide new evidence to support aspects of both the gateway and generalized risk drug use theories. Read

Intoxication by a synthetic cannabinoid (JWH-018) causes cognitive and psychomotor impairment in recreational cannabis users

1/23/21--This study aimed to investigate the acute effects of JWH-018 on several cognitive and psychomotor tasks in participants who are demonstrating representative levels of acute intoxication. Findings indicate that in accordance with previous studies, acute psychomotor and cognitive effects of a relatively low dose of JWH-018 has been demonstrated. Read

Quarterly trends in past-month cannabis use in United States, 2015-2019

2/1/21--Prevalence of cannabis use has been increasing among select subgroups in the US; however, trend analyses typically examine prevalence of use across years. A cross-sectional survey was conducted to determine whether there is seasonal variation in use. Findings indicate that the prevalence of cannabis use increases throughout the year, independently of annual increases. Read

Content analysis of instagram posts by leading cannabis vaporizer brands

10/19/20--According to a study, cannabis vaporizer companies reach thousands of consumers through brand-owned social media accounts. Strategies to promote their products on these channels include posts that may appeal to sociodemographic groups and leveraging social media influencers and other companies to increase overall reach. Read

Mood and cognition after administration of low LSD doses in healthy volunteers

10/17/20--Overall, the study demonstrated selective, beneficial effects of low doses of LSD on mood and cognition in the majority of observations. The minimal LSD dose at which subjective and performance effects are notable is 5 mcg and the most apparent effects were visible after 20 mcg. Read

Burden of cannabis use and disorder in the U.S. veteran population: Psychiatric comorbidity, suicidality, and service utilization

10/14/20--Using data from a nationally representative sample of veterans, a study was conducted to evaluate associations of lifetime cannabis use and CUD with psychiatric problems, suicidality, and treatment utilization. It has been concluded that cannabis use and CUD are associated with substantial psychiatric and suicide-related burden among veterans, highlighting the need for screening, education, and treatment to mitigate potential cannabis-related harm. Read

Does anxiety sensitivity predict addiction severity in opioid use disorder?

9/6/20--Increased anxiety sensitivity (AS), defined as the fear of anxiety-related cognitive, social, and physical symptoms which are misinterpreted as having harmful implications, has shown a relationship with substance use disorders. People with substance use disorders also experience addiction-related problems across several domains of life functioning. Read

E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1

10/28/20--This study provides the first robust scientific evidence to raise awareness regarding the risks of vaping. Read

Does how you use matter? The link between mode of use and cannabis-related risk

9/1/20--With the recent legalization of cannabis there are more cannabis products available to consumers today than ever before. However, little is known about the relation of distinct modes of use to cannabis-related risks. The current study estimated the prevalence of different modes of use among a sample of university students, and quantified the magnitude of association between modes of use (type and number) and cannabis-related risks. Read

Self-reported cannabis use and biomarkers of inflammation among adults in the United States

8/15/20--Data from this nationally representative study suggest potential anti-inflammatory effects of recent cannabis use. Additional studies that biologically measure the THC and CBD concentrations of the cannabis used and employ prospective and or experimental study designs investigate cannabis and inflammation associations are needed. Read

Evaluation of the potential use of cannabidiol in the treatment of cocaine use disorder: A systematic review

9/1/20--The evidence found in this study indicates that CBD is a promising adjunct therapy for the treatment of cocaine dependence due to its effect on: cocaine reward effects, cocaine consumption, behavioral responses, anxiety, neuronal proliferation, hepatic protection and safety. Moreover, clinical trials are strongly required to determine whether the findings in animal models occur in humans diagnosed for cocaine or crack cocaine use disorder. Read

Cannabis use among US adults with anxiety from 2008 to 2017: The role of state-level cannabis legalization

9/1/20--According to study results, cannabis use is increasing among American adults overall, yet is disproportionately common among Americans with anxiety especially among those residing in states where cannabis has been legalized. Read

Perception of cannabis health information labels among people who use cannabis in the U.S. and Canada

6/1/20--This study explored perceptions of cannabis health information labels among people who used cannabis in the last 12 months residing in the U.S. and Canada. Results of the study indicate that respondents living in Canada were less likely to say information was new and rated most messages more believable than those in the U.S. Respondents from legal U.S. states were less likely to say information was new compared to other states. Respondents who used cannabis daily rated acceptability of labels lower (27.8%) than those using 1-48 days (40.6%). Read

Perceived importance of factors in cannabis purchase decisions: A best-worst scaling experiment

5/29/20--This study examined cannabis users’ perceptions of the relative importance of policy-relevant factors when they made cannabis purchase decisions. Results indicate that cannabis users in general perceived product characteristics, quality, and price to be important factors in their willingness to buy cannabis in dispensaries. There were heterogeneities in the perceptions by cannabis use purposes. Read

Pregnancy outcome among women with drug dependence: A population-based cohort study of 14 million births

5/11/20--A study examining the association between drug dependency in pregnancy (DDP) and maternal and newborn outcomes shows an increase in frequency associated with maternal and newborn deaths and adverse events. Further research and public health initiatives have been suggested to be undertaken to address prevention, screening, and treatment. Read

Intensity of cannabis use: Findings from three online surveys

5/1/20--Respondents who reported using cannabis daily (i.e., 30 days in the past month) consumed almost twice as much per day of use on average as did those reporting less than daily. The study finds only modest increases in intensity among those using less than daily, but then a substantial increase (p< 0.001) for those who use daily. Read

Cannabis use during adolescence and the occurrence of depression, suicidality and anxiety disorder across adulthood

4/29/20--According to a longitudinal cohort study over 30-years examining the association between cannabis use in adolescence and the occurrence of depression, suicidality and anxiety disorders during adulthood, young age at first use and high frequency of use in adolescence may particularly increase the risk of depression in adulthood. All associations were independent of cannabis use and other substance abuse during adulthood. Read

Adolescent treatment admissions for marijuana following recreational legalization in Colorado and Washington

5/1/20--There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington following RML. Read

Content analysis of online product descriptions from cannabis retailers in six US states

1/1/20--A current study published in the International Journal of Drug Policy examining how cannabis products are described on US cannabis retailer websites concludes that online cannabis retailers are making potentially unsubstantiated product claims. Future work should examine the potential for these claims to inform consumer behavior. Regulations should ensure that cannabis labeling does not mislead consumers or promote unsafe use. Read

Active cannabis marketing and adolescent past-year cannabis use

11/1/19--According to a study published in Science Direct, youth who engage with cannabis promotions and brands had higher odds of past-year cannabis use. After adjusting for several possible confounders, youth who liked or followed a cannabis business on at least one social media platform had 5 times higher odds of past-year cannabis use. Read

Modes of cannabis use: A secondary analysis of an intensive longitudinal natural history study

6/24/19--There is a paucity of research on modes of marijuana use (e.g., joint vs. blunt), and further, little consensus on how to accurately assess both modes of use and route of administration. A secondary analysis used a longitudinal design with data collected daily to characterize mode of marijuana use. Although the major limitation of this study was use of a convenience sample and lack of detailed data on vaporizer use, results indicate that joint use is no longer the most common mode of use in either White or Black participants and exclusive use of a single modality is uncommon. Read

It’s all the rage! Exploring the nuances in the link between vaping and adolescent delinquency

5/6/19--The findings of a study examining the relationship between vaping different substances and adolescent delinquency while accounting for traditional forms of nicotine and marijuana use suggest that there may be something criminogenic about vaping among adolescents. However, the strength of the relationship between vaping and delinquency is contingent on what is being vaped, with marijuana vaping being most heavily correlated with delinquency. Read

Unintentional pediatric marijuana exposures prior to and after legalization and commercial availability of recreational marijuana in Washington State

3/4/19--According to a study presented in The Journal of Emergency Medicine, reported unintentional pediatric marijuana exposure has increased in the state of Washington since recreational marijuana was legalized, which often presents as altered mental status with unknown cause. As marijuana becomes more available, clinicians should be aware of the risk of unintentional pediatric marijuana exposure, and this should inform lawmakers regarding regulations around childhood exposure to marijuana. Read

Driving under the influence of cannabis among medical cannabis patients with chronic pain

1/9/19--Driving under the influence of cannabis (DUIC) is a public health concern among those using medical cannabis. Understanding behaviors contributing to DUIC can inform prevention efforts. A recent study evaluated three past 6-month DUIC behaviors among medical cannabis users with chronic pain. With more research needed on how to best measure DUIC, prevention messaging for DUIC may be enhanced by addressing alcohol co-consumption. Read

Greater risk for frequent marijuana use and problems among young adult marijuana users with a medical marijuana card

11/25/18--According to a study comparing young adults with and without a medical marijuana (MM) recommendation from a provider (“MM card”) on their developmental trajectories of frequent marijuana use and marijuana-related problems in young adulthood, young adult marijuana users with a MM card had a higher risk profile for marijuana use and related problems compared to those without an MM card. Given expanding state legalization of marijuana for medical use, this issue warrants further attention. Read