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Tobacco and cannabis poly-substance and poly-product use trajectories across adolescence and young adulthood

11/3/21--This study characterized the prevalence, patterns, and racial/ethnic and sex differences of developmental trajectories of use and poly-use of 8 different widely-marketed tobacco and cannabis products across adolescence and young adulthood. Results indicate that over 40% of AYAs (adolescents and young adults) were classified into one of four poly-using trajectories involving use of multiple tobacco and cannabis products, including a sizeable subgroup characterized by substantial increases in poly-use after adolescence. Read

E-cigarette use and change in plans to quit cigarette smoking among adult smokers in the United States” Longitudinal findings from the PATH Study 2014-2019

11/3/21--In this study, U.S. nationally representative data was used to evaluate whether e-cigarette use by smokers initially not planning to ever quit is associated with change in plans to quit. Study results indicate that among adult daily cigarette smokers initially not planning to ever quit, subsequent daily e-cigarette use is associated with subsequent plans to quit smoking. Population-level research on e-cigarette use that is focused on smokers already motivated to quit may limit a complete evaluation of the smoker population. Read

Variations in Electronic Nicotine Delivery System (ENDS) device and association with cigarette quit attempts

11/3/21--This study examined electronic nicotine delivery systems (ENDS) devices classified as disposable, non-refillable cartridge, refillable cartridge, refillable tank, and refillable mod systems and examined if cigarette quit attempts varied by device type among daily and non-daily ENDS users. Read

Prevalence of adolescent cannabis vaping: A systematic review and met-analysis of US and Canadian studies

10/25/21--The findings of this study suggest that the prevalence of cannabis vaping has increased among adolescents in the US and Canada and that more effective preventive and response measures are required. Read

PMPSA’s Population Health Impact Model

9/13/21--Stanton Glantz and his colleagues at the UCSF TCORS submitted this public comment to the FDA stating that the PMPSA’s Population Health Impact Model for IQOS underestimates the health impact of IQOS, does not adequately address new published research and information on population health impacts, and does not demonstrate benefits to individual or population health, so FDA should not issue an exposure modification MRTP order for IQOS 3. Read

FDA can and should prioritize youth over Juul and other e-cigs sales while it ponders the long term

9/10/21--Health groups successfully sued FDA to force action after years of delays and deadline extensions that allowed thousands of e-cigarettes to remain on the market without any FDA premarket review and millions of kids to become nicotine addicts. The order provided that any product that did not submit a PMTA by September 9, 2020, or that had not obtained a permissive marketing order from FDA by September 9, 2021, was being marketed illegally and was subject to enforcement action by FDA. Read

Longitudinal trajectories of E-cigarette use among adolescents: A 5-year, multiple cohort study of vaping with and without marijuana

9/1/21--This longitudinal study sought to identify and differentiate between developmental trajectories of past 30-day e-cigarette use with and without marijuana (i.e., liquid THC) across adolescence (11–19 years old). With one exception, all trajectories of e-cigarette use escalated with age. Moreover, age of onset and progression in use were positively related. The most problematic trajectories, corresponding to more frequent use, were observed among the younger cohorts compared to the oldest. Read

The vapes as strong as 125 cigarettes: Health fears over new craze among young people for super-strength nicotine devices

9/6/21--Health fears are sparked as a result of children buying super-strength vapes – equivalent to smoking 125 cigarettes. They are so powerful that young users have reported lengthy nosebleeds, coughing up blood, headaches, chest pains and dizzy spells. Last night experts warned vaping was a ‘huge crisis for young people’ and called for action. TikTok also launched an investigation after being alerted by the Mail and pledged to ban accounts and remove videos that promoted the possession or consumption of the products by minors. Read

Bernstein Litowitz told to try again in effort to inspect JUUL’s books

8/24/21--Bernstein Litowitz, one of the leading plaintiffs firms for class actions against companies that suffer, drops in their values. They will have to try to make their inspection request again, this time under Delaware law. Grove represents Daniel Grove, who did not waive his rights to inspect corporate records under the California Corporations Code, threatened to bring an action in California to enforce inspection, and JUUL filed a case against Grove in Delaware seeking to declare he had no right to the books. Read

Use of electric cigarettes as a predictor of cannabis experimentation: A longitudinal study among German youth

8/12/21--This study aimed to investigate whether e-cigarette use longitudinally predicts experimentation with cannabis, and results indicate that e-cigarette use is associated with a subsequent initiation of cannabis use. This association seems to be stronger for youth who have a lower risk for substance use in general. Future studies need to investigate whether this is only true for experimental or also more frequent cannabis use. Read

All eyes of FDA: The upcoming regulation of Juul e-cigarettes

8/6/21--Following a court ruling, FDA must issue PMTA orders by September 9, pro or con, for every e-cigarette brand or variant that has applied to stay on the market and take any not receiving permissive orders off the market. So, the big questions are whether FDA will issue PMTA orders to allow the continued marketing of any e-cigarettes, and if so, what restrictions and requirements FDA might put on the permitted e-cigarettes, their flavors, and their marketing. Read

Association of 1 vaping session with cellular oxidative stress in otherwise healthy young people with no history of smoking or vaping

8/9/21--The purpose of this study was to evaluate the association of a single session of ECIG vaping on COS in immune cells in young people who do not smoke or vape compared with young people with long-term TCIG or ECIG use. Read

Young lured to tobacco addiction via e-cigarettes

7/27/21--According to the the World Health Organization (WHO), the tobacco industry's sleek marketing is attracting youngsters to e-cigarettes which can lead to tobacco addiction, despite claims by some executives that they aim to solve the smoking epidemic. The WHO is calling for greater regulation of smoke-free devices containing nicotine. Read

A longitudinal analysis of e-cigarette use and cigar, little cigar or cigarillo initiation among youth and youth adults: 2017-2019

7/28/21--This study was designed to examine whether youth and young adult e-cigarette use is associated with initiation of cigars, little cigars, or cigarillos (CLCCs) and current use of flavored CLCCs. Study results raises new concerns about the effects of e-cigarette use on subsequent combustible tobacco use; therefore, restrictions on CLCCs should be considered in conjunction with current policies designed to reduce the youth vaping epidemic. Read

Goal-setting and positive parent-child relationships reduce risk of youth vaping

7/26/21--Adolescents who set goals for their future and those with strong parental support are less likely to use e-cigarettes and other tobacco products, according to a study by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine physician-scientists. The research, published in the journal Pediatrics, suggests that strategies to prevent youth vaping may be different from what works to dissuade youth from smoking cigarettes. Read

Vaping on TikTok: a systematic thematic analysis

7/23/21--The rising popularity of TikTok among adolescents may influence their awareness and perceptions of e-cigarette use via user-generated content. This study aimed to examine how e-cigarette/vaping-related videos are portrayed on TikTok. Findings from this study illustrated that positively framed e-cigarette and vaping-related postings available without age restrictions on TikTok—a rising video-sharing platform that is popular among adolescents—have been viewed many times. Effective age restrictions are needed to reduce adolescents’ potential exposure to videos that portray vaping positively. Read

Does TikTok push vaping?

7/26/21--To identify vaping-related videos out of the billions posted on TikTok, doctoral student Tianze Sun of the University of Queensland in Saint Lucia, Australia and colleagues searched for hashtags such as #vaping and #vapetricks, as well as one associated with the Juul brand of e-cigarette. They then selected 1,000 with the most page views, eventually discarding 192 that proved to be duplicates or were discovered not to involve vaping despite the hashtags. The most disturbing result from the study is that 20% showed users performing tricks with vaping devices and were also the most viewed by far at 460 million. Read

Juul bought out medical journal for 51K

7/13/21--Juul Labs is facing scrutiny for funding and working on studies of their products, and paying a journal to publish them. Juul teamed up with healthcare consultants Pinney Associates and the Centre for Substance Use Research (CSUR), chiefly, to examine its tobacco vaping device, as FDA weighs whether to grant the company a Premarket Tobacco Product Application (PMTA) as a safer alternative to cigarettes. Read

Webinar: E-cigarettes and vaping – What you need to know

7/6/21--Vaping is becoming an increasing concern for schools and parents, and this webinar will provide up-to-date and relevant information on the research around vaping and trends in use among youth. Information will also be provided on how to best prevent e-cigarette and vaping use among youth. Read

Text message support prompts young adults to quite vaping

7/6/21--Tailored, interactive text messages improved quit rates among young adults using e-cigarettes, a randomized trial in JAMA Internal Medicine reported. The trial’s 2588 participants, aged 18 to 24 years, expressed a strong desire to quit using e-cigarettes. Nearly all vaped daily and had previously attempted to quit. Three-quarters of the participants were current students and more than 80% were White. Read

E-cigarette manufacturers’ compliance with clinical trial reporting expectants: a case series of registered trials by Juul Labs

6/29/21--The reporting of clinical trials sponsored by Juul Labs, the largest e-cigarette company in the USA, is assessed against accepted reporting standards. Findings raise substantial concerns regarding these trials. Clinicians, public health professionals, and the public cannot make informed choices about the benefits or hazards of e-cigarettes if the results of clinical trials are not completely and transparently reported. Clarification and potential enforcement of reporting laws may be required. Read

Juul to pay $40 million to settle N.C. vaping case

6/28/21--Juul Labs has agreed to pay North Carolina $40 million to settle the first of a spate of lawsuits brought by states and localities claiming the e-cigarette company’s marketing practices fueled widespread addiction to nicotine among young people and created a new public health problem. Read

FDA must do more to stop youth vaping, House members say

6/23/21--House members told FDA Acting Commissioner Janet Woodcock, MD, at a hearing on youth vaping that the FDA should be doing more to stop kids from getting addicted to e-cigarettes. Subcommittee chairman Raja Krishnamoorthi (D-Ill.) began the hearing by laying out statistics on the problem and he focused some of his questions on flavored e-cigarettes, noting that the agency's 2020 e-cigarette "flavor ban" included two exemptions: one for tobacco and menthol flavors for Juul and other cartridge-based devices, and another for all flavors of disposable e-cigarettes. Read

New WHO report shows how manufacturers attempt to avoid regulation of e-cigarettes and heated tobacco products

6/21/21--A new WHO report “Litigation relevant to regulation of novel and emerging nicotine and tobacco products: comparison across jurisdictions” offers governments examples of the legal arguments that industry has used in attempts to evade or minimize regulation, as well as how courts have addressed those arguments. Read

Effect of flavor manipulation on ENDS (JUUL) users’ experiences, puffing behavior and nicotine exposure among US college students

6/18/21--This study evaluates the impact of ENDS flavor manipulation on user’s puffing behavior, subjective experience, harm perception and nicotine exposure among college-aged ENDS users. Results of this pilot study provides evidence that ENDS flavors have a substantial effect in enhancing young current ENDS users’ experiences, product appeal and motivation to use the product in the future. It highlights that limiting flavors could play a potential role when designing strategic policies to reduce the appeal of ENDS use among young people. Read

Exposure to JUUL use: cue reactivity effects in young adult current and former smokers

6/18/21--This study examines whether observing the use of this device would elicit similar responses in smokers. Exploratory analyses were also conducted to determine whether JUUL can act as a smoking cue for former smokers. Study results conclude that the use of JUUL affects the user and elicits responses in observers, It is the study first to demonstrate that exposure to JUUL use may act as a smoking cue and exposure to JUUL use may affect tobacco control efforts. Read

Altria-Juul deal goes to trial

6/2/21--Altria Group Inc. and the Federal Trade Commission are squaring off over allegations that the Marlboro maker engaged in anticompetitive practices ahead of its 2018 investment in e-cigarette startup Juul Labs Inc. If the FTC prevails, it could unwind Altria’s 35% interest in Juul. The agency is seeking to force Altria to divest its stake and terminate the companies’ noncompete agreement. The case is being heard by an administrative law judge, who will make an initial decision; the agency’s commissioners will then vote on the matter. Read

JUUL ‘new technology’ pods exhibit greater electrical power and nicotine than previous devices

5/20/21--In 2019, JUUL Labs began marketing in the European Union ‘new technology’ pods that incorporated a new wick that it claimed provided ‘more satisfaction’. In this study,  design and materials of construction, electrical characteristics, liquid composition and nicotine and carbonyl emissions of new technology JUUL pods were compared to their predecessors. Read

An inexpensive intervention to reduce e-cigarette use among young adults

5/17/21--The results of a double-blind randomized clinical trial examining a text messaging intervention that uses cognitive and behavioral coping skills to promote abstinence of e-cigarette use among 18- to 24-year-olds indicate that when compared to the control, the intervention significantly increased the rate of 30-day point prevalence abstinence at 7 months postrandomization (18.6% vs 24.1%). Read

Effectiveness of vaping cessation text message program among young e-cigarette users

5/17/21--In a randomized clinical trial designed to determine the effectiveness of a text message program for vaping cessation among 2588 young adults vs assessment-only control, postrandomization abstinence rates were 24.1% among participants assigned to the text message intervention and 18.6% among participants assigned to an assessment-only control at 7 months, which is a statistically significant difference. No baseline characteristics moderated the treatment-outcome relationship, including nicotine dependence. Read

The youth e-cigarette epidemic: New estimates of JUUL Labs’ revenue from youth users in the US

5/1/21-This study was conducted by creating several scenarios to estimate the percentages of JUUL’s net revenue from adults and youth in the US in 2018. Survey results indicate that a substantial proportion of JUUL’s profits in 2018 were a result of use by youth. It could be required that all e-cigarette companies actively ensure that use by youth is below a pre-determined small fraction of their sales, requiring that a high penalty be paid by those that fail to do so. Read

Ecigs double risk of relapse among former smokers

5/7/21--Laura Barufaldi and her colleagues at the National Cancer Institute of Brazil recently published Risk of smoking relapse with the use of electronic cigarettes: A systematic review with meta-analysis of longitudinal studies that identified six relevant studies from the US, UK and France, three of which have quantitative results. They found that risk of relapse is doubled among former smokers who use e-cigarettes than among non-users. Read

Increases in frequent vaping cannabis among high school seniors in the United States 2018-2019

5/7/21--In a study comparing and examining the prevalence of self-reported frequent vaping of cannabis (defined as using ≥10 times in the past month) between 2018 and 2019 cohorts, frequent vaping of cannabis is increasing among adolescents in the United States, particularly among selected subgroups. Read

Surprise! Juul publishes a paper concluding that e-cigs save lives

4/27/21--A group of Juul scientists have published “Modeling the population health impact of E.N.D.S in the U.S.” that concludes that “the availability of ENDS is projected to reduce smoking and prevent 2.5 million premature deaths by 2100.” Read

E-cigarette users in rural Appalachia develop more severe lung injuries, according to new study

4/20/21--Researchers with the West Virginia University School of Medicine are investigating severe lung injuries occurring among e-cigarette users in rural Appalachia. In a recent study, Sunil Sharma—section chief of pulmonary/critical care and sleep medicine at the School of Medicine—and his colleagues present a case study of patients with EVALI (electronic cigarettes and vaping-associated lung injury) admitted to WVU hospitals from August 2019 to March 2020. Read

Vape seller are using popular music videos to promote e-cigarettes to young people – and it’s working

4/6/21--A recent study uncovered that participants exposed to any electronic cigarette product placement or imagery in music videos were more likely to have used an electronic cigarette in the past month compared to participants with no exposure.the Tobacco Master Settlement Agreement of 1998 prohibits product placement for cigarettes and chew tobacco in television, music videos and motion pictures, but those restrictions do not apply to electronic cigarettes. Read

Democrats urge FDA to clear market of all flavored e-cigarettes

3/23/21--The 43 House Democrats sent the letter to Acting FDA Commissioner Janet Woodcock urging the agency to take all flavored e-cigarettes off the market. The lawmakers want the FDA to ban all flavored e-cigarettes upon further review and nix the exemption the FDA has for methanol and disposable e-cigarettes. Read

Disposable e-cigarette use among U.S. youth – An emerging public health challenge

3/16/21--According to data from the National Youth Tobacco Survey (NYTS), 19.6% of high school students (3.02 million) and 4.7% of middle school students (550,000) reported current (within the preceding 30 days) e-cigarette use in 2020 — 1.8 million fewer than in 2019.2 However, e-cigarette use among youth remains prominent and the landscape of devices is evolving, both of which pose a public health challenge. The changes in device type–specific e-cigarette use during 2019 and 2020 was accessed. Read

Cannabis, vaping, and respiratory symptoms in a probability of U.S. youth

3/3/21--This study provides preliminary evidence that adolescents' cannabis use with Electronic nicotine delivery systems (ENDS) may have negative health consequences. Lifetime cannabis use with ENDS was substantially associated with higher odds of respiratory symptoms. Read

Vaping pot worse than vaping tobacco for teens’ lungs

3/3/21--Teenagers who vape pot are more likely to wheeze and cough than those who smoke or vape nicotine, new survey data reveals. Reports from U.S. kids 12 to 17 show they have a higher risk of wheezing, suffering from a dry cough, and having their sleep, speech or exercise impeded by wheezing if they vape marijuana products, according to results from the U.S. federally funded Population Assessment of Tobacco and Health Study. Read

Vaping pot worse, than vaping tobacco for teens’ lungs

3/3/21-- According to results from the U.S. federally funded Population Assessment of Tobacco and Health Study, teenagers who vape pot are more likely to wheeze and cough than those who smoke or vape nicotine. Survey responses from nearly 15,000 teens showed that vaping pot increased their risk of wheezing or whistling in the chest by 81%, compared with a 15% increased risk from cigarettes and a 9% increased risk from nicotine e-cigarettes. Read

Rules finalized for new tobacco product approvals

3/2/21--Two recently finalized rules provide tobacco product manufacturers with additional information on federal requirements they must meet to get their products on the market. Then-FDA Commissioner Stephen Hahn, MD, said finalization of the rules “is an important milestone in the FDA’s regulation of tobacco products.” Read

What parents need to know about teen vaping and what they can do about it

2/22/21--Vaping among teens has recently skyrocketed, and many believe it is a safe activity. About 1 in 5 high school students vape, exposing them to nicotine, a highly addictive substance found in tobacco. It is recommended that parents talk to their child early about vaping and the facts about the harmful chemicals that people breathe in when they vape. Read

At the speed of Juul: measuring the Twitter conversation to ENDS and Juul across space and time (2017 – 2018)

2/21/21--This study is the first to demonstrate the methodology for constructing county-specific exogenous measure of ENDS-related communication on Twitter and assessing its statistical fitness for use. Results indicate that Juul-related content grew exponentially on Twitter and spread across the entire country during the time when the brand was gaining market share. Read

Chocolate-flavored e-cigarettes are ‘particularly harmful’ to the lungs, study shows

2/10/21--New research shows chocolate-flavored e-cigarettes are "particularly harmful" to the lungs. In fact, scientists found all 10 flavors tested caused some level of toxicity in the cells lining the lungs, resulting in cell death in some instances. The toxins also significantly reduced the ability of immune system cells to remove bacteria and regulate inflammation. Read

Content analysis of cannabis vaping videos on YouTube

2/9/21--There has been an increase in the potency of cannabis during the last two decades and adoption of a novel method of administration—vaping. YouTube, a social media platform, has become a popular source to access cannabis-related information. This study aimed to identify cannabis vaping YouTube videos from 2016 to 2020 and examine the themes and metrics. Read

How a vaping prevention curriculum can help teachers, schools and communities reverse the youth e-cigarette epidemic

1/22/21--Schools and communities have an important role to play in reaching students to make informed choices to pertaining to vaping. Vaping: Know the truth, a national youth vaping prevention curriculum developed as part of Truth Initiative’s nationally recognized youth anti-vaping truth® campaign, gives young people the facts about e-cigarette use and provides resources to quit with This is Quitting, a first-of-its-kind text message program that is already helping nearly 250,000 young people. Read

The youth vaping epidemic: From science to public policy

2/10/21--Even in the midst of Covid-19, teenagers are still vaping in high numbers, putting their health at risk. This youth vaping epidemic highlights the urgent need to understand the science of nicotine addiction and the potential long term health effects of compounds found in vapes. This symposium will convene experts from academic, clinical, public health, and policy communities to discuss new approaches for prevention — with a focus on emerging science to support evidence-based policy recommendations. Read

Recalls and Notifications

1/20/21--HEXO Operations Inc. is voluntarily recalling three SKUs of their all-in-one vape pens due to a hardware defect. This is a voluntary recall due to product quality, in which prolonged auto-ignition may lead to excess heat in the battery cell, which in turn may cause melting of the plastic shell. Please note that HEXO vape distillate, along with HEXO vape cartridge hardware are not impacted by this voluntary recall. Read

California Flavored Tobacco Products Ban Referendum (2022)

1/22/21--The California Flavored Tobacco Products Ban Referendum is on the ballot in California as a veto referendum on November 8, 2022. Proponents of the veto referendum seek to overturn Senate Bill 793 (SB 793), which was signed into law on August 28, 2020 and designed to ban the sale of flavored tobacco products and tobacco product flavor enhancers with a few exceptions. Retailers would be fined $250 for each sale violating the law. Read

How health groups defeated Juul’s effort to rewrite San Francisco’s e-cigarettes regulations

1/23/21--In 2019, Juul undertook an aggressive effort to rewrite San Francisco’s e-cigarette regulations and prohibit the City from enacting new rules without requiring that the new rules be taken to an expensive direct vote of the people. Health groups benefitted from having an established campaign network that recently defended the flavor ban, arguing that Juul’s measure could nullify San Francisco’s prohibition on selling flavored tobacco products. Read

E-cigarettes are NOT safe and vaping harms health, World Health Organization rules

1/22/21--The World Health Organization has issued their latest, hard-hitting warning about vaping and concludes that e-cigarettes are not safe and do increase the risk of heart disease and lung problems. The organization said there is ‘no doubt’ that e-cigarettes are harmful, but said it was too early to tell the long-term impact. Read

Chemicals in e-cigarettes disrupt the gut barrier and trigger inflammation

1/7/21--New research indicates the chemicals found in e-cigarettes disrupt the gut barrier and trigger inflammation in the body, potentially leading to a variety of health concerns. The study found that chronic use of nicotine-free e-cigarettes led to a "leaky gut," in which microbes and other molecules seep out of the intestines, resulting in chronic inflammation. Read

Young people who vape are ‘three times as likely’ to become cigarette smokers later in life

1/11/21--Young vapers are much more likely to become daily cigarette smokers in the future, according to a new study. Researchers have found that 12 to 24-year old vapers were three times as likely to become daily cigarette smokers in the future. Read

Vape store body lobbies government for essential retailer status

1/6/21--Trade body the UK Vaping Industry Association is lobbying government to classify vape shops as essential retailers. The lobbying effort has been ongoing since the first national lockdown in March, but the association has redoubled its efforts, warning that former smokers who have made the switch to electronic alternatives “could be tempted back”. Read

A good time to quit: Smoking and vaping amid COVID-19

1/19/21--Multiple studies have shown that smoking is associated with increased severity of COVID-19 disease. However, because vaping, which is the use of nicotine-containing electronic or e-cigarette products, is relatively new, there is less data. Yet, physicians are adamantly advising patients to do all they can to remain healthy—including not smoking or vaping. Read .

Assessment of nicotine and cannabis vaping and respiratory symptoms in young adults

12/22/20--Findings of this cross-sectional study suggest that cannabis vaping is associated with increased risk of bronchitic symptoms and wheeze in young adults. Further research is needed to understand the temporality of the association and the mechanisms underlying the difference between nicotine and cannabis vaping in the risk of bronchitic symptoms and wheeze. Read

Congress extends ban on mailing cigs to include all e-cigs, including marijuana vapes

12/23/20--The recent legislation Congress passed to fund the government included a provision extending the PACT Act’s prohibition on sending cigarettes through the mail to include e-cigarettes. The law also requires FedEx, UPS and other delivery services to verifying age of the recipient in person and getting a signature before delivering e-cigarettes. Read

Vaping could cloud your thoughts, new studies suggest

12/28/20--Two new studies from the University of Rochester Medical Center (URMC) have uncovered an association between vaping and mental fog. Both adults and kids who vape were more likely to report difficulty concentrating, remembering, or making decisions than their non-vaping, non-smoking peers. It also appeared that kids were more likely to experience mental fog if they started vaping before the age of 14. Read

Underage youth and young adult e-cigarette use and access before and during the coronavirus disease 2019 pandemic

12/3/20--In a national, online, cross-sectional survey study of 2167 youth and young adults using e-cigarettes, 1198 respondents reported changing their amount of e-cigarette use, with 810 reducing or quitting e-cigarette use. During the COVID-19 pandemic, youth e-cigarette users reported changes in e-cigarette use, point-of-purchase, and ability to purchase e-cigarettes without age verification. Read